Pycnogenol®
Pine Bark Extract
Pycnigenol is a natural, French maritime pine bark extract that standardised to 70 ± 5% procyanidins, combining with bioflavonoids and organic acids, with over 160 positive clinical trials. A non-estrogenic hormone balance supplement. It has been affirmed GRAS (Generally Recognized As Safe) for use in conventional foods, based on the evaluation of clinical safety and preclinical toxicology data.
Key Functions & Health Benefits
- Powerful antioxidant support
- Support cardiovascular health
- Support skin health & skin barrier protection
- Relieve menstrual discomfort & endometriosis
- Support UV protection (Photogaing)
- Relieve menopause symptoms
How It Works
- Potent antioxidant and anti-inflammatory activities by inhibits Nf-kB, COX2, 5L, and prostaglandins
- Improves endothelial function (relieves vasoconstriction) by enhances NO production and reduces platelet aggregation
- Reduces α-glucosidase activity and blood glucose levels and improves diabetes related BP,
- Alters messenger RNA (mRNA)/gene expression and stimulate collagen & hyaluronic acid production to improve skin hydration and elasticity
Clinical Evidences
Pycnogenol® intake prevented (i) a decrease in the skin hydration, (ii) transepidermal water loss (TEWL), and (iii) skin darkening in who are working outdoors under considerable environmental stress during the dry autumn season . In addition, Pycnogenol® intake improved (iv) viscoelastic skin properties such as gross elasticity and elastic recovery irrespective of the season.
Potential Side Effects
- Potential Side Effects: May cause dizziness, headache, nausea, or digestive discomfort in some individuals.
- Interaction with Medications: Pycnogenol may interact with blood thinners, diabetes medications, and blood pressure drugs, potentially amplifying their effects.
