Glycerin
Glycerin is a key ingredient in many eye drops, valued for its moisturizing and protective properties. It is a hygroscopic substance, meaning it attracts and retains moisture, which helps to hydrate the ocular surface. By forming a protective barrier, glycerin reduces tear evaporation, alleviates irritation, and improves tear film stability. Its soothing properties make it effective in relieving symptoms of dry eyes, such as burning, stinging, or discomfort. Additionally, glycerin can support healing of minor eye surface damage caused by dryness or irritation, making it a versatile component in artificial tears and lubricating eye drops.
Key Functions & Health Benefits
Humectant – Glycerin attracts and retains moisture, helping to prevent the eye from drying out. Lubricant – Reduce friction and discomfort on the eye surface.
How It Works
The mechanism of glycerin in eye drops involves its hygroscopic property, drawing and retaining water on the ocular surface to hydrate the eyes, while forming a protective barrier that soothes irritation, reduces evaporation, and enhances tear film stability.
Clinical Evidences
This study evaluates the role of glycerin 0.9% as an adjuvant in artificial tears for the treatment of dry eye disease. Conducted as a single-center, randomized, prospective trial, the study compared the effects of carboxymethylcellulose (CMC) 0.5% alone and CMC 0.5% combined with glycerin 0.9% in 60 patients with dry eyes. Results showed significant improvements in tear film break-up time (TBUT) and Schirmer’s test scores in both groups compared to baseline, with the combination formulation providing earlier symptom relief by Day 7. By Day 28, both formulations were equally effective. The study concluded that glycerin enhances the performance of CMC, offering quicker relief for dry eye symptoms.
