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Gut-Brain Axis › The science

The gut-brain axis explained: how your gut affects mood, sleep and stress

A simple guide to the science behind the gut-brain connection, and how psychobiotic strains CCFM1025 and DR7 may support emotional well-being.

Understanding the root

Why you may feel tired, anxious and down

  1. Ongoing stress or past emotional challenges can keep your body on high alert.
  2. Irregular sleep schedules or late nights disrupt your natural body clock.
  3. Low levels of key nutrients like magnesium, B vitamins or omega-3s can affect mood and calmness.
  4. An imbalance in gut bacteria can influence “feel-good” brain chemicals, namely serotonin and GABA.
  5. Digestive discomfort, like heartburn, reflux or gastritis, can add to stress.
  6. Shallow breathing from congestion or poor nasal health can make tension worse.
The connection

What is the gut-brain axis?

40 trillion

Your body hosts about 40 trillion bacteria, more than the number of human cells. Together, these microbes form your gut microbiome.

Scientists call the digestive system the “second brain” because your gut and brain are in constant two-way communication through the gut-brain axis. This connection goes beyond digestion. It can influence your:

MoodStressSleep
Chemical balance

How your gut can affect mood and anxiety

Serotonin & melatonin

About 90% of your body’s serotonin, a key mood-supporting chemical, is produced in the gut and later converted into melatonin to help regulate sleep.

GABA & calmness

Gut bacteria also influence GABA, the brain’s main calming chemical, helping reduce tension and support emotional balance.

Circadian rhythm

The gut keeps its own daily rhythm, working with your brain’s master clock to support restful sleep and modulate stress responses.

Balanced gut

A balanced gut helps regulate inflammation, so your nervous system doesn’t stay on high alert, and helps keep worry and tension in check.

Scientific insights

How psychobiotics support you

Psychobiotics are probiotics for mental well-being: good bacteria that interact with your nervous system through chemical messengers such as serotonin, GABA and dopamine, helping to support emotional balance and regulate stress.

Certain strains don’t just support digestion. They can also help:

  • Produce neurotransmitters such as serotonin and GABA
  • Reduce stress-related inflammation
  • Modulate stress responses

Research is still emerging. Studies suggest psychobiotics work best as part of a holistic approach, alongside healthy sleep, nutrition and lifestyle habits, not as a replacement for them.

Bifidobacterium breve

CCFM1025
  • Shown to improve mood and emotional balance
  • Better digestive comfort, with less bloating, indigestion and irregular bowel symptoms
  • Enhanced sleep quality and fewer sleep disturbances
  • Supports healthy cortisol (stress hormone) levels, with a potential calming effect

Lactobacillus plantarum

DR7
  • Shown to lower stress and anxiety levels
  • Helps modulate the body’s stress response
  • Helps improve overall emotional well-being
  • Supports focus, memory and learning

Find both strains in Lang Bragman GB-Axis

CCFM1025 and DR7 together, vegetarian friendly, with no added sugar or preservatives.

References (25)
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  3. Bonaz B, Bazin T, Pellissier S. The vagus nerve at the interface of the microbiota–gut–brain axis. Front Neurosci. 2018;12:49.
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This page is not intended to diagnose, treat, cure or prevent any disease, and is not a substitute for professional medical advice. An educational initiative by Lang Bragman, managed and operated by Pharm-Dx.

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